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Cecile Kremer
HIV-1 remains a major global health problem, and in countries with mature generalized epidemics such as Uganda there are groups of individuals that are more disproportionately affected. Among these groups in Uganda are fishing communities, which also have extensive sexual networks bridging into the general population. This modelling study investigates the impact of combined HIV prevention interventions on HIV dynamics in these high-risk fishing communities. A deterministic compartmental model was calibrated to the observed HIV prevalence among these fishing communities obtained from a 2016 census, using an active learning approach. The model was then used to examine the impact of different combinations of prevention interventions on HIV prevalence.