Jornal de doenças infecciosas e terapia

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A Short Commentary on Temporal Dynamics of Subclinical Malaria in Different Transmission Zones in Myanmar

Poe Poe Aung, Khin Thet Wai

The role of ultrasensitive Polymerase Chain Reaction (usPCR) in detecting low-density infections compared to conventional Rapid Diagnostic Tests (cRDT) amid the doubtful field applicability of advanced molecular laboratory methods in resource poor settings. The article demonstrated the vital role of testing in border areas and identifying high risk groups and hot spots by point-of-care diagnostics. Moreover, Glucose 6-phosphate dehydrogenase deficiency is alarming when using primaquine for radical cure of P.vivax infections. The hsRDT is capable of detecting subclinical malaria in low transmission settings but is limited by the controversial issue of its costeffectiveness.