Sistema Gastrointestinal e Digestivo

Abstrato

An Open Comparative Randomized Clinical Study of Plant Based Drugs Embelia Robusta Roxb and Mallotus Philippinensis Muell on Intestinal Parasites

Shishira Bharadwaj, Shraddha Nayak and Joshi VK

Background: Intestinal parasites are common cause of morbidity.

Aim: To compare the efficacy and safety of two plant based drugs Embelia robusta Roxb and Mallotus philippinensis Muell on intestinal parasites.

Methods: Forty Patients exhibiting symptoms of parasitic infection were diagnosed and confirmed by stool test. They were then randomized to either Embelia in a dose of 5 g or Mallotus in dose of 1 g with honey and jaggery as adjuvant respectively. Drugs were administered for a period of one week and follow-up was carried in 15 days and thereafter a month to observe symptomatic relief and presence or absence of ova/cyst in stool sample examination.

Results: Symptomatic relief was found in Mallotus while some symptoms still persisted with Embelia. Embelia robusta had 40% cure rate while Mallotus had 70% cure rate, but both the drugs did not result in any adverse effects.

Conclusions: It was observed that Mallotus philippinensis had better efficacy.