Jornal de Biorremediação e Biodegradação

Abstrato

Application of Monooxygenases in Dehalogenation, Desulphurization, Denitrification and Hydroxylation of Aromatic Compounds

Pankaj Kumar Arora, Alok Srivastava and Vijay Pal Singh

Monooxygenases act as biocatalysts in bioremediation process and synthetic chemistry due to their highly regioselectivity and sterioselectivity on wide range of substrates. They are involved in the process of desulfurization, dehalogenation, denitrification, ammonification, hydroxylation, biotransformation and biodegradation of various aromatic and aliphatic compounds. In the recent years, the practical applications of monooxygenases have been improved using the approaches of directed evolution, meta-genomics and bioinformatics. This review is focused on current applications of monooxygenses especially in biodegradation and biotransformation of aromatic compounds.