Sistema Gastrointestinal e Digestivo

Abstrato

Considerations on Some Problems in Carcinoid Research

Jun Soga

Three points of emphasis unrelated to each other are described. First: Detailed mechanism of the earliest carcinoid formation in the form of a budding phenomenon is clearly demonstrated in a colored photo of consective serial sections of the gastric gland. Second: The original drawing of the submucosal nodule for which the term “carcinoid” was proposed as a benign tumor is pointed out to be a result of malignant invasion of neoplastic cells originating in the mucosa and penetrating the muscularis mucosae. Third: Based on the concept that the term “carcinoid” is a misnomer, an alternative term “endocrinocarcinoma (ECC)” is roposed.