Jornal de Pesquisa e Terapia de Dependência

Abstrato

Drugs for Alzheimer's

Gonzalo Emiliano Aranda-Abreu, María Elena Hernández-Aguilar, Marisol Herrera-Rivero and Luis Isauro García-Hernández

Five drugs are currently approved for the treatment of Alzheimer’s disease; nevertheless, we have faced the challenge to respond to family members of these patients the reason why they observe a limited improvement from these treatments. Although both acetylcholinesterase inhibitors and memantine are correctly designed and they show an adequate performance, we believe the neuronal conditions resulting from the pathophysiology of the disease difficult their proper working in brains affected with Alzheimer’s. Patients should therefore undergo a neuronal rehabilitating therapy that enables these drugs for a more effective performance.