Medicina Tradicional e Naturopatia Clínica

Abstrato

Effect of Serially Diluted Drug Digitalis purpurea on Modulation of Anesthetized Consciousness of Indian Bufomelanostictus

Anup Sharma and Bulbul Purkait

Concept prevails amongst believers that serially diluted drugs do not produce any side effect. The modus operandi of the serially diluted drugs is through neural network. The practitioners of different systems of medicine with paradigmatic differences use the same drug substance in different dilution to treat patients with contrary clinical conditions, Digitalis purpurea is one such drug. The present work describes the effect of ultra-diluted drug Digitalis purpurea and Digoxin on modulation of Diethyl ether induced anesthesia in Indian Bufomelanostictus. Diethyl ether and rectified spirit (also used as diluent for ultra-dilution) are used as controls in this experimental work. In this preliminary study, it is found that the reflex and anesthetic action of Digitalis purpurea 200 is similar to rectified spirit probably because of the simple dilution of the active ingredient. Digitalis purpurea 30 was found to be more effective than rectified spirit. Digitalis purpurea 30 produced the longest period of anesthesia while Digoxin reduced duration of anesthesia. Both Digitalis purpurea 6 and Rectified spirit were effective for almost same duration. The ultra-diluted drug samples and digoxin were further analyzed by Cyclic Voltammetry and Fluorescence spectroscopy which establishes the cause and effect relationship.