Jornal da doença de Alzheimer e parkinsonismo

Abstrato

Epidermal Growth Factor (EGF) is Associated with Memory and Executive Functioning in Progressed Parkinson's Disease

Travis H Turner, Ann-Charlotte Granholm, Amy Duppstadt-Delambo, Heather Boger, Guttalu Kumaraswamy and Vanessa Hinson

Objectives: Epidermal Growth Factor (EGF) is a candidate biomarker for cognitive functioning in Parkinson’s disease (PD). Relationships between EGF and cognition were explored in progressed PD. Methods: EGF levels were obtained from a heterogeneous sample of PD patients referred for clinical neuropsychological evaluation. Correlation and effect size analyses evaluated relationships between EGF and cognitive measures. Results: EGF was associated with measures of executive functioning and memory. Conclusion: EGF corresponds to cognition in progressed PD. Findings are consistent with previous studies, and support further investigation of EGF’s utility as a biomarker for cognitive functioning in PD