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Exercise Approaches to Ameliorate Fatigue in People with Multiple Sclerosis

Mehendale K and Aruin AS

Objective: People with multiple sclerosis (MS), a chronic disease of the central nervous system without a known cure, often experience fatigue that affects their quality of life. The goal of this article was to review the available literature on the role of different intervention modalities’ efficacy in reducing the effects of fatigue in patients with MS.

Methods: We reviewed 47 studies available in PubMed, Academic Search Premier (EBSCO host) and Cochrane databases until March 2013 that focus on the role of the mind and body approach and exercises in minimizing fatigue in individuals with MS.

Results: The reviewed studies showed the effectiveness of Yoga, Tai Chi and neurocognitive exercises based interventions in ameliorating levels of fatigue and improving quality of life in individuals with MS.

Conclusions: This focused review suggests that a variety of approaches involving Mind and Body interventions and exercise modalities can be used individually or in combination to deal with fatigue in individuals with MS. The review also provides a basis for further research focused on evaluation of the effectiveness of each of these modalities in resolving the effects of fatigue in patients with MS.