Câncer de mama: pesquisa atual

Abstrato

Expression and Viability of Tamoxifen-Resistant Breast Cancer Cells

Jianfang Cao

Movement of 78-kDa glucose-controlled protein from endoplasmic reticulum to plasma film addresses a change in outlook past its conventional capability as an ER chaperone protein. Cell surface GRP78 applies novel flagging capabilities, and instruments basic its cell surface articulation are simply arising. Obtained tamoxifen obstruction of bosom malignant growth cells is went with raised degree of csGRP78. Subsequently, the tamoxifen-safe MCF7 bosom malignant growth cells addresses a clinically pertinent model to concentrate on components of csGRP78 articulation.