Jornal Internacional de Inflamação, Câncer e Terapia Integrativa

Abstrato

Genetics of Skin Cancer Diagnostics and Treatment.

Dr. Muzamil S

Diseases evolve side by side with human evolution and play significant role in health.
Along with the societal and technological development, mankind also faces great
challenges in health sector. One of these challenges is the changes in disease
manifestation, its cure and obviously its effect on living organisms especially humans,
which has worsen as time progresses. Some of the diseases are easily treatable now
while other still poses complications. Skin cancer is one of the most common and
widespread cancers despite technological and medicinal advancements and demands
persistent attention. It is categorized into different types according to its location of
origination and usually these cancers do not spread to other body parts. Various
environmental and genetic factors contribute in its occurrence, development and
metastasis. People with blonde skin tone are at supreme risk to be affected by
melanoma. Considering the importance of this disease, the current review
concentrates on the various types of skin tumors, its manifestations, the causes behind
disease development and treatment. Genetical mutations in somatic cells or at fetus
level play major role in its establishment. Furthermore, environmental factors also
affect the normal cellular pathways by bringing about the alterations at gene level.
Prudent analysis of the genetics may lead to better understanding of the key genes
involved in its establishment and thus, the pertinent knowledge can be utilized in
designing painless and accurate diagnostic approaches and advanced targeted
therapies.