Jornal Internacional de Inflamação, Câncer e Terapia Integrativa

Abstrato

Guardians of Health: Immune Cells in the Battle against Tumorigenesis

Thiaul Isaacs

In the intricate realm of cancer development, the interplay between immune cells and tumorigenesis takes center stage. This abstract delves into the dual roles played by immune cells, acting both as vigilant guardians and potential turncoats in the face of tumorous challenges. The dynamic equilibrium between the immune system and burgeoning cancer cells is explored, unraveling the complexities that influence disease progression. From the initial recognition and eradication of aberrant cells to the potential exploitation of immune evasion mechanisms by tumors, this abstract navigates the delicate balance that shapes the fate of tumorigenesis. Key players, such as T cells, macrophages, and regulatory cells, emerge as central figures in this biological drama, orchestrating a symphony of responses that can either suppress or promote tumor growth. Furthermore, the abstract scrutinizes the molecular and cellular dialogues that define the immune landscape within the tumor microenvironment. It sheds light on immunosuppressive factors employed by tumors to subvert the immune response and examines emerging therapeutic strategies aimed at bolstering the immune system's anti-cancer prowess. Ultimately, this abstract serves as a gateway to understanding the intricate relationship between immune cells and tumorigenesis, offering insights that may pave the way for novel therapeutic interventions and a deeper comprehension of the ever-evolving battle between the immune system and cancer.