Jornal Internacional de Inflamação, Câncer e Terapia Integrativa

Abstrato

Inflammation Disclosing the Basic Arsenal of the Body's Defense Mechanism

Qin Han Carrie

Inflammation, a fundamental component of the body's defense mechanism, serves as a complex and highly regulated response to various stimuli, ranging from infections to tissue injuries. This intricate process involves a symphony of cellular and molecular players working in unison to restore homeostasis. At its core, inflammation aims to eliminate the initial cause of cell injury, clear out damaged cells and tissues, and initiate tissue repair. Key protagonists include immune cells such as neutrophils and macrophages, which migrate to the site of injury or infection, releasing signaling molecules like cytokines. Blood vessels play a crucial role, undergoing changes to facilitate the influx of immune cells. While acute inflammation is a protective and localized response, dysregulation can lead to chronic inflammation implicated in various diseases. Understanding the nuanced interplay within the body's inflammatory arsenal holds promise for therapeutic interventions and sheds light on the delicate balance between protection and pathology.