Ciências Marinhas: Pesquisa e Desenvolvimento

Abstrato

Isolation of New Hexapeptides?JBIR-39 and JBIR-40?from a Marine Sponge-Derived Streptomyces sp. Sp080513SC-24

Ikuko Kozone, Miho Izumikawa, Keiichiro Motohashi, Aya Nagai, Masahito Yoshida, Takayuki Doi, Motoki Takagi and Kazuo Shin-ya

Streptomyces sp. Sp080513SC-24 was isolated from a marine sponge, Haliclona sp., which is inhabited by diverse Actinobacteria , and then its culture was comprehensively searched for secondary metabolites. New two hexapeptides, JBIR-39 (1), and -40 (2), were isolated from the fermentation broth of Sp080513SC-24. The structures of 1 and 2 were elucidated on the basis of 1D and 2D NMR spectroscopy and MS analyses.