Jornal de Diabetes e Prática Clínica

Abstrato

Neglected Factor during Cancer Progression by Hyperglycemia

Laura Soysal

Recent data from sizable cohort studies shows that persons with type 2 diabetes have a greater cancer incidence. The probable causes of this relationship are yet unknown, though, as of this writing. These glucosehungry cells may get extra glucose from hyperglycemia, the most significant aspect of diabetes, which also leads to oncogenesis, apoptosis resistance, and chemotherapy-resistant tumour cells [1]. The impact of hyperglycemia on the advancement of cancer in cancer patients with abnormal blood glucose levels should not be disregarded given the link between diabetes and malignancies [2]. In this article, we discuss the role that hyperglycemia plays in the development of cancer and its management, as well as how it might influence the phenotypic of cancer cells and promote drug resistance. Consequently, managing hyperglycemia may Hyperglycemia, also known as high blood glucose, is a condition that occurs when there is either an insufficient quantity of insulin in the body or when the body is unable to properly utilise the insulin that is present [3].