Doenças Neuroinfecciosas

Abstrato

Neuroprotective Effect of Exogenous Melatonin on Apoptosis of Noradrenergic Neurons in Locus Coeruleus of Adult Male Rats After REM Sleep Deprivation

Somaye Mesgar, Aghaie A, Jameie SB, Sadeghy Y

Sleep as a widespread physiological phenomenon is seen in all vertebrates. In primates as human, the sleep consists of two components Rapid eye movement (REM) & non-REM. One of the major centers involved in the control of REM sleep is Locus Coeruleus (LC). REM sleep deprivation causes neural death in the LC. In the present study, we administered melatonin as an antioxidant factor and neuroprotective agent to prevent neural death.