Arquivos de ciência

Abstrato

Physiological Mechanisms of Drug Actions and Therapeutics

David Dhalli

The world of medicine has been fundamentally transformed by the development and application of pharmaceutical drugs. A profound understanding of the physiological mechanisms underlying drug actions is paramount for effective therapeutics. This abstract provides a concise overview of the intricate processes by which drugs exert their effects on the human body. It explores the fundamental principles of drug action, including receptor binding, enzyme inhibition, ion channel modulation, and transporter interference. Additionally, the diverse types of drug actions, from agonists to antagonists and partial agonists to inverse agonists, are examined. Importantly, individual variability and drug response are discussed, highlighting the significance of pharmacogenomics in tailoring drug treatments to individual genetic profiles. The knowledge of physiological mechanisms behind drug actions continues to drive advancements in personalized medicine, offering hope for more effective and safer therapies, and a brighter future for healthcare.