Sistema Gastrointestinal e Digestivo

Abstrato

Protocol for Three Dimensional Histopathological Examination of the Vermiform Appendix in Neuroendocrine Tumors

Samir Ghani, Pradeep Hamal

The conventional protocol for dissection of the vermiform appendix in the Surgical Pathology laboratory allows two dimensional (2-D) histopathological examination of the tip of the appendix. In this report, a new three dimensional (3-D) approach is described, to allow thorough (360 degree) histopathological examination of the entire serosal surface and muscular wall of the tip of the appendix. This is designed to deal with neuroendocrine (NE) tumors that may present at this anatomical location as a routine daily case in every histopathology department. To our knowledge, this approach has not been described in the literature of NE tumors of the appendix.