Jornal de Diabetes Clínica

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Rabbits Lacking Cr Macular Pigment Epithelium

Hu Hang

Rabbits, as lagomorphs, possess a unique eye anatomy characterized by the absence of macular pigment epithelium (MPE) in the Cr’s, unlike other mammals. The MPE is a crucial component of the retina responsible for protecting the macula and supporting high-resolution central vision. This absence raises questions about the implications for rabbit vision and the compensatory mechanisms they may have developed. While rabbits lack MPE, their macula is rich in cone cells, emphasizing peripheral vision rather than focused central vision. Rabbits may have evolved alternative adaptations to mitigate potential damage from blue light and oxidative stress, such as their crepuscular activity pattern and the presence of a tapetum lucidum. However, the lack of protective measures against blue light and oxidative stress may render their retinal cells more vulnerable. Further research into the unique eye anatomy of rabbits and their compensatory mechanisms could provide valuable insights into retinal protection and the trade-offs associated with different visual strategies among species.