Jornal Internacional de Inflamação, Câncer e Terapia Integrativa

Abstrato

Renal cell carcinoma (RCC) epidemiology and genetic variation, risk factor-based primary and secondary prevention with early detection with a focus on biomarkers

James A Harker*

Renal cell carcinoma (RCC), with 400,000 diagnoses and 180,000 deaths in 2020, represents 2.4% of all cancer diagnoses globally industrialised nations with the greatest rates of sickness, particularly in Europe and North America.As more nations adopt Western lifestyles, incidence is expected to rise in the future. In addition to intervening variables like smoking, obesity, hypertension, diabetes, nutrition, and alcohol, RCC risk factors also include fixed characteristics like gender, age, and inherited disorders. The development of early diagnostic techniques, knowledge of prenatal risk factors, and intervening measures in primary prevention are crucial for RCC. The epidemiology of RCC, risk factors,and biomarkers implicated in lowering incidence and enhancing survival will all be covered in this review.