Jornal de Metalurgia do Pó e Mineração

Abstrato

Review on a Nanomaterials Mechanisms-Induced Oxidative Stress and Toxicity

Geetha N, Prabhavathi G, Ayeshamariam A*, Beevi AH, Punithavelan N, Uthiram C and Jayachandran M

The review reveals the recent trends of nano-materials in biomedical applications and an overview to discuss the commercialization of nano-materials. Due to innovative ideas in nano-materials created a lot of new discoveries in the medical, consumer sectors and industrial applications. The properties of nano-materials lead to a quite interest in a various applications in biomedical field such as structural and physicochemical properties. In a biological activity; toxicities of a nanoparticle are frequently reported. In the presence of acellular factors such as size, composition, particle surface and presence of metals in a nano-materials induces oxidative stress and it creates a pathway for patho physiological effects includes fibrosis, genotoxicity and injuries in a skin. Zinc oxide acts as an antioxidant for reducing oxidative stress and it acts as a protective agent for an immune system in a biomedical fields. This review summarizes biomedical applications of a nano-materials and the role of an oxidative stress.