Jornal de doenças infecciosas e terapia

Abstrato

Short Communication about Interactions between the RNA-Binding Protein IGF2BP1 and Tumorigenic Viruses

Markus Glaß, Stefan Hüttelmaier

Viral infections are responsible for a significant proportion of human cancers. Virus propagation as well as infection-induced tumorigenesis rely on interactions with host factors. The review published in Viruses summarizes the current knowledge about the collaborations between the oncofetal RNA-binding protein IGF2BP1 and distinct tumorigenic viruses. The interplay between IGF2BP1 and viruses can support pro-proliferative traits of the infected cells but can also augment the propagation of the virus.