Sistema Gastrointestinal e Digestivo

Abstrato

Skeletal Muscle Metastasis Secondary to Adenocarcinoma of Colon: A Case Report and Review of Literature

Mutahir A Tunio, Mushabbab AlAsiri, Khalid Riaz, Wafa AlShakwer, Muhannad AlArifi

Introduction: Colon adenocarcinoma frequently metastasizes to the liver, regional lymph nodes, lungs and peritoneum. However, metastasis to the skeletal muscles is extremely rare manifestation of colon adenocarcinoma. To date, only few cases have been reported in the literature. Skeletal muscle metastasis from colon adenocarcinoma usually remains asymptomatic or manifest as swelling and are associated with dismal prognosis. Case presentation: A 28 years old Saudi man known case of adenocarcinoma of transverse colon treated with extended hemi-colectomy and chemotherapy one year back, presented with abdominal wall swelling and right buttock swelling since 8 months. Physical examination revealed right gluteal mass of size 3×2 cm and abdominal wall mass of size 2×2cm. Rest of examination was unremarkable. Computed tomography-Positron emission tomography (CT-PET) showed 3×2 cm lobulated mass arising from gluteus maximus muscle and another mass in rectus abdominis muscle. Incisional biopsy confirmed the metastatic adenocarcinoma of colon. Patient subsequently underwent palliative radiotherapy followed by systemic chemotherapy. At time of publication, patient was alive with progressive disease. Conclusion: Skeletal muscles metastases are rare manifestation of adenocarcinoma of colon and searching for the primary focus in a patient with skeletal muscle metastasis, colon cancer should be considered as differential diagnosis.