Toxicologia: Acesso Aberto

Abstrato

Tetanus Toxin

Micael Holger

Tetanus toxin (TeNT) is a bacterial protein poison created by Clostridium tetani. Consequent to entering the circulation system, TeNT ties with high partiality to a receptor complex at the neuromuscular intersection. Neurospecific restricting of TeNT includes the cooperation with polysialogangliosides of the G1b series, like GT1b and GD1b , and glycosylphosphatidylinositol-moored proteins, including Thy-1. TeNT disguise requires the honesty of film microdomains, and it is gone before by the horizontal arranging of TeNT from the lipid part of its receptor complex.