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The Clinical Profile of Migraine: Since The Molecular Changes Until The Semiological Manifestations

Silvia García, María Karina Vélez Jiménez, Sofía Lizeth Alcaraz Estrada, Sergio Sauri Suárez, Sandra Quiñonez Aguilar, Paul Mondragón Terán, Asisclo de Jesús Villagómez Ortiz, Juan Antonio Suárez Cuenca and Ildefonso Rodríguez Leyva

Migraine is a common and incapacitating neurological disorder affecting 10 to 20% of the world population; it is more common between females from 20 to 40 years old.

The objective of this paper is to carry out a brief, analytic, and practical review of migraine through a vision of connecting molecular to clinical perspectives. Migraine was an approach as a primary neuronal network disorder, and some controversial topics were analyzed. New pieces of knowledge have provided innovative possibilities for effective management for intractable cases, and it allows a better understanding of migraine complications.