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Abstrato

Treatment of Lichen Planus: A Comparative Study

Vibha Singh, Garima Singh, Mahesh Pal and Kaninika Tandon

Introduction: Lichen planus is a relatively common disorder, estimated to affect 0.5% to 2.0% of the general population. It is a chronic inflammatory disease affecting mucosal and cutaneous tissue. Oral lichen planus occurs more frequently than the cutaneous form and tends to be more resistant to any treatment.

Material and methods: This study was conducted in Department of Oral Maxillofacial Surgery. Patients in study who were clinically diagnosed and histo- pathologically confirmed as patients of oral lichen planus, were included in the study, Informed consent was taken from all patients. The extract of Turmeric and Tulsi with glycerine base in ointment form was made at National Botanical research institute Lucknow. It was used for local application twice/day for a period of 3 months. Exclusion criteria included systemic diseases and pregnancy. All the patients were divided into two groups, first group was treated with turmeric and second group was treated with Tulsi. All the patient were instructed to report after every 2 weeks for check up and to collect ointment. Evaluation was done on the basis of clinical symptoms like burning sensation, intolerance to spicy food, redness, ulceration, strai and pain. The data was collected, tabulated and analyzed.

Results: Our results shows significant improvement in all clinical features of the lichen planus. Tulsi shows better result in halitosis. On other hand Turmeric is better in reducing burning sensation, pain and white lesions.

Conclusion: Turmeric and Tulsi both are effective in management of Oral lichen planus but turmeric is more effective in reducing burning sensation, pain and white lesions compared to Tulsi.