Imunologia: Pesquisa Atual

Abstrato

Unexpected Connections to the Immune System

Dr. Angyang Cao

Epigenetics is an rising field, due to its significance within the control of a wide extend of organic forms. The Su(Var)3–9, Enhancer-of-zeste and Trithorax (SET) and Myeloid, Brazen, and DEAF-1 (MYND) domain-containing (SMYD) proteins, named SMYD1, SMYD2, SMYD3, SMYD4 and SMYD5, are proteins that catalyse methylation of histone and non-histone substrates, subsequently playing a key part in quality expression control in numerous organic settings, such as muscle improvement and physiology, haematopoiesis and numerous sorts of cancer. This audit centers on a generally unexplored perspective of SMYD family individuals - their connection with immunology. Here, immunology is characterized within the broadest sense of the word, counting fundamental investigate on macrophage work or have insusceptibility against pathogen disease, as well as clinical considers, most of which are centred on blood cancers.