Pesquisa do Journal of Mucosal Immunology

Abstrato

Unraveling the Complexities of Mucosal Inflammation: From Immune Responses to Therapeutic Insights

Rosil Yuso

Unraveling the complexities of mucosal inflammation is of paramount importance to comprehend the intricate immune responses and discover potential therapeutic avenues for various inflammatory disorders. This abstract delves into the multifaceted immunological mechanisms governing mucosal inflammation, exploring the pivotal roles of immune cells, such as T lymphocytes, macrophages, and dendritic cells, in orchestrating the inflammatory cascade within the respiratory, gastrointestinal, and urogenital tracts. The review highlights the delicate balance between proinflammatory and anti-inflammatory cytokines, essential in maintaining mucosal homeostasis. Dysregulation of this equilibrium can lead to chronic ailments like asthma, inflammatory bowel disease, and urinary tract infections. Moreover, recent advances in molecular and cellular research have unveiled promising therapeutic targets for intervention. By understanding the fundamental processes driving mucosal inflammation, researchers and clinicians can develop novel and targeted therapies to mitigate the burden of inflammatory diseases and enhance the overall quality of life for affected individuals. This abstract serves as a stepping stone towards improved diagnostics and personalized treatments, fostering advancements in the field of mucosal immunology.