Jornal de Farmacologia Celular e Molecular

Abstrato

Antimetastatic Mechanisms of Bisdioxopiperazine Compound Study, A Gateway to Success

Da-Yong Lu, Jian Ding, Rui-Ting Chen, Bin Xu, Nagendra Sastry Yarla and Ting-Ren Lu

Neoplasm metastasis is the causality of 90% cancer patient’s mortality. Bisdioxopiperazine compounds (Biz compounds) are a series of synthetic agents that are firstly discovered to exhibit antimetastatic efficacy to animal tumor models. In order to completely overcome neoplasm metastasis in clinics, antimetastatic therapeutic study for Biz compounds is of great clinical significance. This editorial highlights these researches from new perspective.